Combination Chemotherapy in Treating Patients With Previously Untreated...
Condition: SarcomaInterventions: Biological: dactinomycin; Biological: filgrastim; Biological: sargramostim; Drug: cyclophosphamide; Drug: topotecan hydrochloride; Drug: vincristine...
View ArticleCombination Chemotherapy in Treating Patients With Stage III or Stage IV...
Conditions: Ovarian Cancer; Primary Peritoneal Cavity CancerInterventions: Drug: carboplatin; Drug: gemcitabine hydrochloride; Drug: paclitaxel; Drug: pegylated liposomal doxorubicin...
View ArticleS0101 Gemcitabine and Irinotecan in Treating Patients With Metastatic or...
Conditions: Esophageal Cancer; Gastric CancerInterventions: Drug: gemcitabine hydrochloride; Drug: irinotecan hydrochlorideSponsors: Southwest Oncology Group; Southwest Oncology Group;...
View ArticleErlotinib and Irinotecan in Treating Patients With Advanced Solid Tumors
Condition: Unspecified Adult Solid Tumor, Protocol SpecificInterventions: Drug: erlotinib hydrochloride; Drug: irinotecan hydrochlorideSponsors: National Cancer Institute (NCI); Mayo Clinic;...
View ArticleComparison of IV Topotecan/Docetaxel to Docetaxel Alone in Second-Line Stage...
Conditions: Non-Small-Cell Lung Cancer; Lung Cancer, Non-Small CellInterventions: Drug: Topotecan/Docetaxel combination; Drug: DocetaxelSponsors: GlaxoSmithKline; GlaxoSmithKlineCompleted -...
View ArticleGemcitabine and Irinotecan in Treating Patients With Cancer of Unknown Primary
Condition: Carcinoma of Unknown PrimaryInterventions: Drug: gemcitabine hydrochloride; Drug: irinotecan hydrochlorideSponsors: National Cancer Institute (NCI); North Central Cancer Treatment...
View ArticleIrinotecan, Oxaliplatin, and Capecitabine in Treating Patients With...
Condition: Unspecified Adult Solid Tumor, Protocol SpecificInterventions: Drug: capecitabine; Drug: irinotecan hydrochloride; Drug: oxaliplatinSponsors: National Cancer Institute (NCI);...
View ArticleSequentially Administered CPT-11 and Mitomycin C in Patients With Advanced...
Conditions: Esophageal Cancer; Esophagus Cancer; Cancer of Stomach; Stomach CancerInterventions: Drug: CPT-11; Drug: Mitomycin CSponsors: Ohio State University Comprehensive Cancer...
View ArticleIntravenous Weekly Topotecan In Subjects With Recurrent Or Persistent...
Conditions: Neoplasms, Endometrial; Endometrial CancerIntervention: Drug: topotecanSponsors: GlaxoSmithKline; GlaxoSmithKlineCompleted - verified June 2012
View ArticleActive Symptom Control Alone Or In Combination With Oral Topotecan In...
Conditions: Lung Cancer, Small Cell; Small Cell Lung CancerIntervention: Drug: topotecanSponsors: GlaxoSmithKline; GlaxoSmithKlineCompleted - verified June 2012
View ArticlePhase 1/1b Dose Escalation Study Evaluating BSI-201 as a Single Agent and in...
Condition: TumorsInterventions: Drug: BSI-201 (iniparib); Drug: irinotecanSponsors: Sanofi-Aventis; Sanofi-Aventis; BiPar SciencesCompleted - verified May 2012
View ArticleStudy of Melphalan and Topotecan (MT) Followed by Autologous Stem Cell Rescue...
Condition: Multiple MyelomaInterventions: Drug: melphalan; Drug: topotecan; Procedure: Bone Marrow TransplantSponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt...
View ArticleIrinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy in Treating...
Condition: Small Intestine CancerInterventions: Drug: capecitabine; Drug: irinotecan hydrochloride; Drug: oxaliplatinSponsors: National Cancer Institute (NCI); North Central Cancer...
View ArticleAZD2281 and Irinotecan in Treating Patients With Locally Advanced or...
Condition: Colorectal CancerInterventions: Drug: irinotecan hydrochloride; Drug: olaparibSponsors: NCIC Clinical Trials Group; NCIC Clinical Trials GroupActive, not recruiting - verified July...
View ArticleHigh-Selenium Brassica Juncea, Irinotecan, and Capecitabine in Treating...
Condition: Unspecified Adult Solid Tumor, Protocol SpecificInterventions: Dietary Supplement: high-selenium Brassica juncea; Drug: capecitabine; Drug: irinotecan hydrochlorideSponsors: City...
View ArticlePhase I/II Combination With Irinotecan- Erbitux
Condition: Metastatic Colorectal Cancer (MCRC)Interventions: Drug: Cetuximab; Drug: Irinotecan; Drug: Brivanib; Drug: Brivanib; Drug: Brivanib PlaceboSponsors: Bristol-Myers Squibb;...
View ArticleBusulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in...
Conditions: Solid Tumor; Adult Central Nervous System Germ Cell Tumor; Adult Rhabdomyosarcoma; Childhood Central Nervous System Germ Cell Tumor; Childhood Soft Tissue Sarcoma; Ewing...
View ArticleTopotecan, High-Dose Cyclophosphamide, Carboplatin, and an Autologous...
Conditions: Ovarian Cancer; Peritoneal Cavity CancerInterventions: Biological: filgrastim; Drug: carboplatin; Drug: cyclophosphamide; Drug: topotecan hydrochloride; Procedure: autologous...
View ArticleEfficacy Study of Chemotherapy to Treat Ovarian Cancer Recurrence by...
Condition: Ovarian CancerInterventions: Drug: stealth liposomal doxorubicin; Drug: carboplatin; Drug: paclitaxel; Drug: Topotecan; Drug: GemcitabineSponsors: National Cancer Institute,...
View ArticleIrinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma...
Condition: Malignant GliomasInterventions: Drug: Irinotecan; Drug: LenalidomideSponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Celgene CorporationRecruiting - verified...
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